Allonnia

Boston, MA, USA

Competitive advantage associated with cleaner and more energy efficient waste processing combined with opportunity for remediation driving a paradigm shift amongst manufacturers.

Possess an Industry-leading database of genetically sequenced and functionally characterised microbes and enzymes for biotransformation or biogeochemical sequestration.

Leverage access to Ginkgo Bioworks’ codebase to scan for promising genetic analogs of naturally occurring biochemical pathways effective in remediation.

Capability to engineer customizable and traceable microbes, creating environments to stimulate and measure trillions of mutations

Also leveraging microbes to synthesis enzymes that operate on the directly on waste chemistry

Focus on rare earth elements Oil Sands Process Water (OSPW) ,PFA) and Polyurethane foam

Third company to launch out of the Ginkgo Bioworks' investment vehicle to leverage biology to solve global intractable problems, also funded by Bill Gates' Cascade Investments

Asimov

Boston, MA, USA

Building the first CAD platform for biology, an end-to-end platform for genetic design by integrating state-of-the-art synthetic biology with computational tools, a cloud-based software suite for genetic designers that is coupled with real biological components and data-driven models

Enabling the design and manufacture of advanced therapies; biologics, viral vecors, programmable medicines

Genetic Simulator software makes predictions about the biophysical behavior of the system, whilst debugging capacity tells you what's actually happening 'under the hood' of an engineered cell to find the root cause of the problem and guide the design of a better genetic program that achieves the desired behavior.

Standardized chassis serve as a controlled environment for genetic part characterization.

Aiming to provide a comprehensive set of engineering-grade parts, to control diverse aspects of cell biology.

Ginkgo Bioworks

Boston, MA, USA

Horizontal platform; across cell type and industrial applications.

Codebase of DNA logic is derived undertaking projects, held as a unique proprietary database, can be leveraged in further application.

Focus on high throughput, parallel capabilities in design, generation, experimentation and testing enables the profiling of thousands of biological designs. Endpoint improvements are realised though this power of exploring a large combinatorial design space.

Range of services make up the foundry:

• Strain development

• Metabolic engineering

• Advanced compute and data

• Enzyme discovery

• Cell Engineering

• Pathway assembly

• High-throughput analytical assays

Leverage services through wide ranging partnerships:

• Fragrances - Robertet

• Programmable medicines - Synlogic

• Vaccines - Aldevron

• Agriculture, nitrogen fixation optimization - Agricultural Bayer

• Cannabinoid, enzyme Discovery - Cronos

• Foods, protein production - Motif Foodworks

• Biosecurity - Concentric

• Biosurveillance - IARPA

• Nucleic acid medicines

Colorifix

Norwich, UK

Discover colours in nature

Apply DNA sequencing to find the genes encoding pigment expression

Engineered microorganism are provided to clients who ferment on site the microorganiism

Expressed dye is used directly in standard dye machines

Vastly reduced CO2, energy, water and use of toxic chemicals

Aim for economical competitiveness

Amyris

Emeryville, CA, USA

Lab-to-Market operating system has successfully produced genetically engineering molecules, bioidentical to those that exist in nature.

The synthetic biology platform can create any molecule that exists in nature.

Ingredient pipeline consists of hundred of thousands of molecules with diverse functionality that can be leveraged in novel applications

Thirteen ingredients already commercialised, continue to leverage the pipeline for exploring other molecules and applications.

Can access over half of all small molecule diversity in nature.

Ferment with sustainably-sourced sugarcane .

Ferementation process signfiicantly more environmentally friendly than enbcumant chemistry. Two ingredients, squalane and squalene are currently derived from deep sea shark livers, an unsustainable source.

Own brands and industry partnerships with a focus on clean chemistry